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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NCL
All Species:
16.36
Human Site:
Y473
Identified Species:
36
UniProt:
P19338
Number Species:
10
Phosphosite Substitution
Charge Score:
0.4
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P19338
NP_005372.2
710
76614
Y473
E
K
G
Q
N
Q
D
Y
R
G
G
K
N
S
T
Chimpanzee
Pan troglodytes
XP_516145
1006
108719
Y745
E
K
G
Q
N
Q
D
Y
R
G
G
K
N
S
T
Rhesus Macaque
Macaca mulatta
XP_001116949
938
100743
Y701
E
K
G
Q
N
Q
D
Y
R
G
G
K
N
S
T
Dog
Lupus familis
XP_850477
699
75739
Y462
E
K
G
Q
S
Q
D
Y
R
G
G
K
N
S
T
Cat
Felis silvestris
Mouse
Mus musculus
P09405
707
76705
E474
G
E
K
G
Q
R
Q
E
R
T
G
K
T
S
T
Rat
Rattus norvegicus
P13383
713
77129
E476
G
E
K
G
Q
R
Q
E
R
T
G
K
N
S
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509329
631
67414
S416
K
S
Q
G
L
E
N
S
R
G
G
K
N
N
A
Chicken
Gallus gallus
P15771
694
75622
Q448
D
Y
T
G
E
K
S
Q
Q
E
S
Q
K
G
G
Frog
Xenopus laevis
P20397
651
70177
N406
E
K
S
Q
N
S
G
N
K
K
G
P
E
G
D
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_797746
400
43419
E228
D
D
E
E
D
S
D
E
E
D
A
P
P
A
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P27476
414
44517
D242
D
G
R
P
I
N
C
D
M
S
T
S
K
P
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
70.3
74.7
91.6
N.A.
83.9
84.2
N.A.
65.6
63.2
55.6
N.A.
N.A.
N.A.
N.A.
N.A.
24
Protein Similarity:
100
70.4
75.4
94.9
N.A.
90.1
90.4
N.A.
73.9
76
68.4
N.A.
N.A.
N.A.
N.A.
N.A.
32.8
P-Site Identity:
100
100
100
93.3
N.A.
33.3
40
N.A.
33.3
0
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
100
N.A.
46.6
53.3
N.A.
60
26.6
40
N.A.
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
23.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
35.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
10
0
0
10
19
% A
% Cys:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% C
% Asp:
28
10
0
0
10
0
46
10
0
10
0
0
0
0
10
% D
% Glu:
46
19
10
10
10
10
0
28
10
10
0
0
10
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
19
10
37
37
0
0
10
0
0
46
73
0
0
19
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
10
46
19
0
0
10
0
0
10
10
0
64
19
0
10
% K
% Leu:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
37
10
10
10
0
0
0
0
55
10
0
% N
% Pro:
0
0
0
10
0
0
0
0
0
0
0
19
10
10
0
% P
% Gln:
0
0
10
46
19
37
19
10
10
0
0
10
0
0
0
% Q
% Arg:
0
0
10
0
0
19
0
0
64
0
0
0
0
0
0
% R
% Ser:
0
10
10
0
10
19
10
10
0
10
10
10
0
55
0
% S
% Thr:
0
0
10
0
0
0
0
0
0
19
10
0
10
0
55
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
10
0
0
0
0
0
37
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _